SimHeart©

offers a virtual laboratory for recordings of heart contractions in the Langendorff set-up in response on the most relevant transmitters and drugs,
including a drug laboratory for the adjustment of the appropriate solutions.



Featured experiments:

Effects of Adrenaline and Acetylcholine on frequency and amplitude of heart contractions
(inotroph and chronotroph effects), effects of competitive receptor blockers Propranolol and Atropine,
adrenaline dose-response curve and its shift by the ß-blocker Propranolol (competitive inhibition),
comparison with non-competitive inhibition by the Ca2+-channel blocker Verapamil,
strengthening of the contractions by the heart-glycoside g-Strophantine,
induction and treatment of arrhythmias and heart blocks in systole and diastole.
for details see Tutorial and Protocol form
download a fully functioning DEMO Version